Allogeneic (Donor Cell) Biologics at the Karli Health Institute
At Karli Health Institute, we are proud to integrate next-generation biologic therapies to support advanced healing, vitality and performance. Working under Florida’s newly adopted stem-cell law (CS/CS/SB 1768), which allows licensed physicians to offer certain stem-cell and perinatal biologic products for orthopedics, wound-care and pain-management with full, informed patient consent (Florida Senate) - we are proud to partner with ZEO ScientifiX to bring ethically-sourced, high-quality cellular product solutions to our patients.
What We Offer
Allogeneic Products (Donor-Derived Biologics)
- Umbilical Cord-Derived Stem Cells: ZEO’s product line includes vials of umbilical-cord stem cells (e.g., 10 million or 20 million live cells), sourced from healthy-birth tissue, designed for structural support and long-term regeneration support in areas such as joint and soft-tissue injury, wound healing and pain management. (zeoscientifix.com)
- Perinatal-Derived Exosome Concentrates: Tiny, cell-secreted particles (extracellular vesicles) derived from umbilical-cord or amniotic-fluid sources. Examples include:
- Umbilical-Cord Exosomes: 25 billion EV or 200 billion EV formulations; indicated for joint pain, wound healing support, pain relief and aesthetic support.
- Amniotic-Fluid Exosomes: Formulations ranging from ~25 billion up to ~500 billion EV, for orthopedic, wound-care, pain and aesthetic applications. These donor-derived (“allogeneic”) options allow us to select advanced biologics that have been processed under cGMP, ethically sourced and batch-tested for viability and identity.
Autologous Products (Patient’s Own Biologics)
- PPX™ Autologous Exosome Concentrate: Using your own blood, the PPX process isolates and concentrates extracellular-vesicle fractions (exosomes) from your platelets. This personalized biologic is designed to deliver high-density regenerative signaling using your own cellular material. We offer this product in varying doses, 100 Billion, 200 Billion and 400 Billion EV formulations ZEO. This autologous option can be used in place of or in addition to conventional platelet-rich-plasma (PRP) and bone marrow concentrate (BMC) treatments and is designed for orthopedic, pain, aesthetic and advanced regenerative protocols.
How It Works – Simple Terms
Initial Assessment & Consent
- We review your medical history, treatment goals, and clearly explain the nature of the biologic therapies — including that these are not (yet) FDA‐approved for all uses, but are offered under Florida law with informed consent.
Biologic Selection
- Based on your condition (joint degeneration, wound, pain, aesthetic goal), we select the appropriate biologic option best suited to you: for example, donor-derived umbilical-cord stem cells or your own autologous PPX exosome concentrate.
Treatment Administration
- The biologic is administered in a clinically controlled setting via injection into the joint, wound site, tissue or other location. Post-treatment protocols (rehab, follow-up) are tailored.
Monitoring & Follow-Up
- We monitor your progress with functional assessments, biomarkers or imaging as needed. Our goal is to integrate these biologics into a broader regenerative-health program that supports you now and into the future.
Why Choose These Products?
- High Quality & Ethical Sourcing: ZEO’s products are processed in FDA-registered, cGMP-compliant facilities, batch-tested for sterility, viability and identity in accordance with Florida law. (zeoscientifix.com)
- Versatility: Whether you chose your stem cells and exosomes (autologous) or donor-derived (allogenic), we tailor biologics to your specific regenerative need - orthopedic related (joint, tendon, soft-tissue), pain, wound or aesthetic.
- Regulated in Florida: Under SB 1768 (effective July 1, 2025) Florida-licensed physicians may administer these types of biologic therapies for orthopedics, wound care and pain management, provided comprehensive informed consent is obtained. (flmedical.org)
- Patient-Centered: Your treatment plan is crafted specifically for you, with robust consent processes, clear explanation of risks, benefits and alternatives, and follow-up to measure outcomes.
Important Considerations
- These biologic treatments are FDA unapproved and investigational in nature and uses are not validated for safety and efficacy by rigorous clinical trials.
- While the products are processed under high-quality laboratory conditions, individual responses vary. We commit to transparent dialogue about expected outcomes, timeframe and risk/benefit trade-offs.
- As part of our premium regenerative medicine program, we integrate these biologics with diagnostics, functional medicine, lifestyle optimization, monitoring and follow-up to maximize your long-term regenerative-health strategy.
