Regenerative Medicine · Miami, FL
PRP Therapy in Miami
Karli Health is led by Harvard-trained physician, researcher and published author David Karli, MD, MBA.
Platelet-rich plasma, or PRP, uses concentrated components from your own blood to support the body’s repair response. At Karli Health, PRP preparations can be customized to target a specific platelet concentration or total platelet dose based on each patient’s needs.
The Therapy
What Is PRP Therapy?
Platelet-rich plasma is created from a small sample of the patient’s own blood. The blood is processed to separate and concentrate key components, including platelets and, when appropriate, white blood cells. These components release proteins and signaling factors involved in the body’s healing and repair response.
Bone Marrow Concentrate
Autologous
Your own bone marrow cells, concentrated and characterized before treatment.
Explore Bone Marrow Concentrate
Umbilical Cord Cell Therapy
Allogeneic
Ethically sourced donor cells used under Florida law, with full sourcing and screening standards.
Explore Umbilical Cord Cell TherapyHow PRP Is Created
PRP is produced by separating whole blood into three layers:
Karli Health utilizes manual processing techniques in an on-site laboratory with data-refined protocols to carefully collect the platelet-rich portion then customize the preparation according to the physician’s treatment plan.
What Makes Karli Health’s PRP Different?
Our PRP is different because the process is built around the Karli Standard.
Karli Health does not take a one-size-fits-all approach to PRP. The preparation can be customized to target a specific platelet concentration or total platelet dose.
What Is the Difference Between Leukocyte-Rich and Leukocyte-Poor PRP?
Two commonly used PRP formulations are leukocyte-rich PRP, which contains a higher concentration of white blood cells, and leukocyte-poor PRP, in which white blood cells are minimized. Greyledge data have identified meaningful differences in patient-reported outcomes between leukocyte-rich and leukocyte-poor PRP for certain orthopedic applications, including differences in functional improvement, pain reduction and durability of response. Which formulation is selected depends on the tissue, diagnosis and treatment goal. Dr. Karli discusses these differences and why one formulation may be chosen over another for a specific application.
The team utilizes Greyledge Technologies’ technology to customize and dose your specific product in an on-site laboratory at the time of your procedure. This ability to measure, adjust, and confirm the final product in real time is highly specialized and not customary in most regenerative medicine practices.
When this technology is utilized, it enables our team to measure platelet counts and verify that the finished product is within the intended treatment parameters.
Patient-reported outcomes are then tracked through the Greyledge Data Cloud and used to refine treatment protocols over time.
Across Karli Health and other U.S. practices using Greyledge technology, the Greyledge Data Cloud has tracked more than 8,000 regenerative treatments as of August 2026, and that number grows every day as new treatments are added. Patient follow-up extends beyond two years and is ongoing. This multi-practice dataset allows treatment variables such as preparation and dose to be compared with patient-reported outcomes over time.
That’s the Karli Standard in practice: know what was administered, know the dose, and connect it to the patient’s outcome over time.
That’s care that is measured, personal, and fit for you.
Common Areas PRP Is Used
Explore Areas of Care
What the PRP Procedure Involves
A typical PRP procedure begins with a standard peripheral blood draw. Your blood is measured to establish a baseline platelet and cell count, then manually processed in Karli Health’s on-site laboratory using Greyledge technology to concentrate and customize the PRP preparation, including the intended leukocyte profile. The finished product is remeasured to confirm the final preparation and dose before treatment. PRP is then injected into the treatment area using ultrasound guidance and fluoroscopy when needed to support accurate placement.
Who May Be a Candidate for PRP?
PRP is well established and studied over the last 20+ years, but it may not be the best therapy for every patient or every condition. We thoroughly discuss candidacy based on your diagnosis, symptoms, imaging findings, prior treatments, medications, goals, and the physician's evaluation.
Cost and Insurance
PRP cost depends on the condition being treated, the number of injections needed, and the complexity of the procedure. At Karli Health, the typical price range for joint PRP is $1,500–$3,000. The typical price range for spine PRP is $3,000–$8,000, depending on the disease state, number of spinal levels, and number of treatment areas. PRP is generally less expensive than other cellular therapies, such as stem cell therapy. Whether PRP or a stem cell therapy is more appropriate depends on the diagnosis, tissue being treated, severity of the condition, prior treatment, goals and physician evaluation.
Regenerative medicine procedures, including PRP, are generally not covered by insurance, and all Karli Health services are self-pay.
Frequently Asked Questions About PRP Therapy
PRP, or platelet-rich plasma, uses concentrated components from a patient’s own blood, especially platelets, to support repair signaling and the body’s healing response. PRP has been widely studied for its safety and clinical outcomes.
Yes. PRP is autologous, meaning it is created from your own blood. A standard blood draw is performed in the office, then processed to create the PRP preparation.
The PRP procedure typically takes about one to one and a half hours, including consent, blood draw, processing, and injection.
Yes. PRP may be evaluated for joint, tendon, ligament, and sports-related conditions depending on the diagnosis and physician assessment. At Karli Health, we commonly evaluate PRP for knee, hip, shoulder, and small-joint pain.
Regenerative medicine procedures, including PRP, are generally not covered by insurance, and all Karli Health services are self-pay.
Related regenerative therapies
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Open Umbilical Cord Cell TherapyMUSE Cell Therapy
A distinct donor cell type with published research and tracked patient outcomes.
Open MUSE Cell TherapyLOOK. FEEL. PERFORM GREAT.
Considering PRP Therapy?
Schedule a consultation with Karli Health to learn whether PRP or another regenerative medicine option may be appropriate for your condition, goals, and overall health.
Medically reviewed by David Karli, MD, MBA · Harvard-trained physician, researcher and published author
Last reviewed: September 30, 2026